Description

D-Chlorprenaline Hydrochloride is a high-purity chiral intermediate and active pharmaceutical ingredient (API) of significant commercial importance. Its primary value lies in its role as a key building block for the synthesis of advanced pharmaceutical compounds, particularly those targeting respiratory and cardiovascular conditions. This product is essential for research institutions, pharmaceutical development laboratories, and manufacturers engaged in the production of specialized adrenergic agents. We supply D-Chlorprenaline Hydrochloride CAS NO 33404-81-8 to the global market with a commitment to stringent quality control and reliable supply chain logistics.

Application

• Pharmaceutical Intermediate: Critical chiral precursor in the synthesis of β-2 adrenergic agonists and related therapeutic agents.
• Active Pharmaceutical Ingredient (API): Used in the formulation of specific bronchodilator and decongestant medications.
• Biochemical Research: Serves as a standard or reagent in pharmacological studies investigating adrenergic receptor mechanisms.
• Asymmetric Synthesis: Employed as a starting material or resolving agent in chiral synthesis due to its defined stereochemistry.
• Reference Standard: Utilized in analytical laboratories for method development and quality control testing of pharmaceutical products.

Basic Information

Item	Details
Product Name	D-Chlorprenaline Hydrochloride
CAS No.	33404-81-8
Molecular Formula	C9H13Cl2NO
Molecular Weight	222.11 g/mol
Synonyms	(1R,2S)-2-Amino-1-(3,5-dichlorophenyl)propan-1-ol hydrochloride; (-)-Chlorprenaline hydrochloride; D-(-)-Chlorprenaline HCl; (R,R)-Chlorprenaline hydrochloride; 1-(3,5-Dichlorophenyl)-2-aminopropan-1-ol hydrochloride (D-form); NSC 113926; α-[(1R,2S)-2-Amino-1-hydroxypropyl]-3,5-dichlorobenzyl alcohol hydrochloride
EINECS	Contact for details

Quality Control

Our D-Chlorprenaline Hydrochloride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical applications. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, impurities, and other critical parameters. Our processes are designed to support compliance with cGMP and relevant ICH guidelines for API manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.