Description

2-(Methylthio)Iodobenzene is a versatile organosulfur and organoiodine compound, serving as a key synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a methylthio and an iodine substituent on the benzene ring, makes it a valuable building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and heterocycle synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing aryl sulfide or biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the aryl iodide moiety enables efficient coupling reactions.
• Cross-Coupling Reactions: Serves as an excellent substrate in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of organic electronic materials and polymers.
• Chemical Biology Probes: Utilized to synthesize tagged molecules or probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-(Methylthio)Iodobenzene
CAS No.	33375-94-9
Molecular Formula	C7H7IS
Molecular Weight	250.10 g/mol
Synonyms	1-Iodo-2-(methylthio)benzene; 2-Iodophenyl Methyl Sulfide; o-(Methylthio)iodobenzene; (2-Iodophenyl)(methyl)sulfane; Methyl 2-iodophenyl sulfide; 2-Methylthioiodobenzene; 2-Iodoanisole, thio-; Benzene, 1-iodo-2-(methylthio)-
EINECS	Contact for details

Quality Control

Every batch of 2-(Methylthio)Iodobenzene is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Light yellow to amber liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.