Description

2'-[(Trimethylsilyl)Oxy]Propiophenone is a specialized organosilicon compound featuring a trimethylsilyl-protected hydroxyl group on a propiophenone backbone. This compound matters as a versatile protected intermediate and synthetic building block, enabling precise chemical transformations in sensitive environments. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and fine chemical industries for the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where hydroxyl group protection is required.
• Organic Synthesis Reagent: Used in advanced organic reactions, including Grignard additions, alkylations, and as a precursor for more complex ketone derivatives.
• Chemical Research & Development: Serves as a critical starting material or protected intermediate in academic and industrial R&D for novel compound libraries.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials.
• Silicon Chemistry Studies: Used as a model compound in studying silyl ether chemistry and protection/deprotection strategies.

Basic Information

Product Name	2'-[(Trimethylsilyl)Oxy]Propiophenone
CAS No.	33342-87-9
Molecular Formula	C12H18O2Si
Molecular Weight	222.36 g/mol
Synonyms	1-[2-[(Trimethylsilyl)oxy]phenyl]-1-propanone; 2-(Trimethylsiloxy)propiophenone; o-Trimethylsiloxypropiophenone; Propiophenone, 2'-[(trimethylsilyl)oxy]-; 2-Hydroxypropiophenone trimethylsilyl ether; TMS-protected 2-hydroxypropiophenone
EINECS	Contact for details

Quality Control

Our 2'-[(Trimethylsilyl)Oxy]Propiophenone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.