Description

2,6-Dichloropyridine-4-Thiol is a versatile sulfur-containing heterocyclic building block with significant synthetic utility. This compound is valued for its dual reactive sites, the thiol group and halogenated pyridine ring, which enable its use in constructing complex molecular architectures. It is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand Precursor: Serves as a starting material for the synthesis of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials, dyes, and photoactive compounds.
• Chemical Research: A valuable building block in organic synthesis for constructing complex pyridine-thioether derivatives and heterocyclic systems.

Basic Information

Product Name	2,6-Dichloropyridine-4-Thiol
CAS No.	33256-13-2
Molecular Formula	C5H3Cl2NS
Molecular Weight	180.06 g/mol
Synonyms	4-Mercapto-2,6-dichloropyridine; 2,6-Dichloro-4-pyridinethiol; 2,6-Dichloro-4-mercaptopyridine; 4-Pyridinethiol, 2,6-dichloro-; 2,6-Dichloropyridine-4-thione (tautomer); 2,6-Dichloro-4-thiopyridone
EINECS	Contact for details

Quality Control

Our 2,6-Dichloropyridine-4-Thiol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.