Description

4-(Chloromethyl)-n-(4-Methylphenyl)-1,3-Thiazol-2-Amine Hydrochloride is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a critical building block in the development of active pharmaceutical ingredients (APIs) and specialized agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality raw materials for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiazole moiety contributes to biological activity.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic compounds and reaction methodologies.
• Material Science: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand Preparation: Useful for synthesizing specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(Chloromethyl)-n-(4-Methylphenyl)-1,3-Thiazol-2-Amine Hydrochloride
CAS No.	33188-18-0
Molecular Formula	C11H12ClN2S • HCl
Molecular Weight	275.61 g/mol
Synonyms	4-(Chloromethyl)-N-(p-tolyl)-1,3-thiazol-2-amine hydrochloride; 2-Amino-4-(chloromethyl)-N-(4-methylphenyl)thiazole hydrochloride; 4-(Chloromethyl)-2-[(4-methylphenyl)amino]-1,3-thiazole hydrochloride; N-(4-Methylphenyl)-4-(chloromethyl)-1,3-thiazol-2-amine hydrochloride; 33188-18-0; p-Tolyl-[4-(chloromethyl)thiazol-2-yl]amine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-n-(4-Methylphenyl)-1,3-Thiazol-2-Amine Hydrochloride is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.