Description

(S)-4-[4-(Boc-Amino)Butyl]Oxazolidine-2,5-Dione CAS NO 33043-60-6 is a high-purity, chiral oxazolidinedione derivative, serving as a critical protected intermediate in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of the (S)-4-aminobutyl moiety into complex molecular architectures, which is essential for constructing pharmacologically active compounds. This building block is indispensable for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• Peptidomimetic Chemistry: Used to incorporate constrained, turn-inducing elements into peptide backbones to enhance stability and bioavailability.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of selective enzyme inhibitors.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct molecules with defined chirality for high-value fine chemicals.
• Bioconjugation & Linker Chemistry: The Boc-protected amino group and reactive dione moiety allow for selective functionalization and linker attachment in bioconjugate and prodrug development.
• Academic & Contract Research: A valuable reagent for medicinal chemistry research and discovery programs in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	(S)-4-[4-(Boc-Amino)Butyl]Oxazolidine-2,5-Dione
CAS No.	33043-60-6
Molecular Formula	C₁₂H₂₀N₂O₅
Molecular Weight	272.30 g/mol
Synonyms	(S)-4-(4-((tert-Butoxycarbonyl)amino)butyl)-1,3-oxazolidine-2,5-dione; (S)-Boc-4-Aminobutyl-oxazolidinedione; (S)-N-Boc-1,4-diaminobutane-2,5-dione cyclic carbamate; (S)-4-(4-(Boc-amino)butyl)-2,5-oxazolidinedione; 2,5-Oxazolidinedione, 4-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]-, (4S)-; Boc-Abu(Oxz)-OH (cyclic form); (S)-Boc-Dab-Oxz
EINECS	Contact for details

Quality Control

Our (S)-4-[4-(Boc-Amino)Butyl]Oxazolidine-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.