Description

4-Bromo-1-Butanol is a versatile brominated alcohol intermediate with significant utility in organic synthesis. Its bifunctional nature, featuring both a reactive bromine atom and a primary hydroxyl group, makes it a valuable building block for constructing more complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring butyl chain elongation or functionalization.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the bromobutyl moiety is incorporated.
• Polymer & Material Science: Serves as a monomer or chain transfer agent in the synthesis of specialty polymers, coatings, and liquid crystals.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions (SN2) to introduce the 4-bromobutoxy group, and in cyclization reactions to form oxygen-containing heterocycles like tetrahydrofurans.
• Ligand & Catalyst Preparation: Useful for modifying ligands and creating functionalized catalysts for asymmetric synthesis and cross-coupling reactions.
• Chemical Research & Development: A fundamental reagent in medicinal chemistry and process chemistry for scaffold diversification and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Bromo-1-Butanol
CAS No.	33036-62-3
Molecular Formula	C4H9BrO
Molecular Weight	153.02 g/mol
Synonyms	4-Bromobutanol; 4-Bromobutan-1-ol; 1-Hydroxy-4-bromobutane; 4-Bromobutyl alcohol; ω-Bromobutyl alcohol; Tetramethylene bromohydrin; Butanol, 4-bromo-; NSC 60548
EINECS	251-350-1

Quality Control

Our 4-Bromo-1-Butanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC and HPLC, to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for extended stability. The product is moisture-sensitive; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (20°C)	1.40 - 1.45 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.