Description

1,2,3,4-Tetrahydro-8-Isoquinolinol Hydrochloride is a versatile heterocyclic building block and key synthetic intermediate in organic chemistry. Its value lies in its functionalized isoquinoline core, which is integral to constructing complex molecular architectures for pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential therapeutic agents, particularly those targeting the central nervous system (CNS).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing.
• Academic & Institutional Research: Employed in medicinal chemistry programs and biochemical studies to explore new chemical entities and their biological activities.
• Ligand and Catalyst Development: The nitrogen-containing heterocycle can be utilized to develop novel ligands for metal catalysis or as a core structure in organocatalysts.

Basic Information

Product Name	1,2,3,4-Tetrahydro-8-Isoquinolinol Hydrochloride
CAS No.	32999-38-5
Molecular Formula	C9H12ClNO
Molecular Weight	185.65 g/mol
Synonyms	8-Hydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydroisoquinolin-8-ol hydrochloride; 8-Hydroxy-THIQ HCl; THIQ-8-ol HCl; 1,2,3,4-Tetrahydro-8-hydroxyisoquinoline hydrochloride; 8-Hydroxy-1,2,3,4-tetrahydroisoquinoline HCl; 8-Hydroxy-THIQ hydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-8-Isoquinolinol Hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.