Description

3-Bromo-5-Chlorobenzo[B]Thiophene is a high-purity halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of pharmaceuticals and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated thiophene core.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic semiconductors and charge-transport materials for OLEDs and OFETs.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	3-Bromo-5-Chlorobenzo[B]Thiophene
CAS No.	32969-26-9
Molecular Formula	C8H4BrClS
Molecular Weight	247.54 g/mol
Synonyms	3-Bromo-5-chlorobenzo[b]thiophene; 5-Chloro-3-bromobenzo[b]thiophene; 3-Bromo-5-chloro-1-benzothiophene; Benzo[b]thiophene, 3-bromo-5-chloro-; 32969-26-9; 3-Br-5-Cl-benzothiophene
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chlorobenzo[B]Thiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.