Description

1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Methyl Ester is a versatile and high-value heterocyclic building block essential for advanced organic synthesis. This compound is critical for research and development in the pharmaceutical sector, serving as a key precursor for the synthesis of complex bioactive molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Alkaloid Synthesis: Serves as a key starting material for the synthesis of complex tetrahydroisoquinoline alkaloids and their analogs.
• Agrochemical Development: Employed in the research and synthesis of novel active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: Acts as a building block for creating specialty chemicals, dyes, and advanced materials.

Basic Information

Product Name	1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Methyl Ester
CAS No.	32909-74-3
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	Methyl 1,2,3,4-tetrahydroisoquinoline-1-carboxylate; 1,2,3,4-Tetrahydro-1-isoquinolinecarboxylic acid methyl ester; 1-Carbomethoxy-1,2,3,4-tetrahydroisoquinoline; Methyl tetrahydroisoquinoline-1-carboxylate; 1-Methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline; THIQ-1-COOMe; 1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid, methyl ester
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to support your research and regulatory needs. Certificates of Analysis (COA) are available for every batch upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.