Description

(S)-(+)-1,2,3,4-Tetrahydro-1-Naphthylamine is a high-purity, single-enantiomer chiral amine building block of significant importance in asymmetric synthesis. Its defined stereochemistry is critical for imparting specific biological activity and desired physical properties in advanced pharmaceutical intermediates. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed reactions, enabling the production of enantiomerically pure compounds.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced materials requiring precise stereochemical control.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-(+)-1,2,3,4-Tetrahydro-1-Naphthylamine
CAS No.	32908-38-6
Molecular Formula	C10H13N
Molecular Weight	147.22 g/mol
Synonyms	(1S)-1,2,3,4-Tetrahydro-1-naphthalenamine; (S)-1-Amino-1,2,3,4-tetrahydronaphthalene; (S)-1,2,3,4-Tetrahydro-1-naphthylamine; (S)-1-Tetralinamine; (S)-α-Tetralylamine; (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine; (S)-1,2,3,4-Tetrahydro-naphthalen-1-ylamine
EINECS	Contact for details

Quality Control

Our (S)-(+)-1,2,3,4-Tetrahydro-1-Naphthylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0% ee
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.