Description

Diethyl (Methoxymethyl)Phosphonate is a versatile organophosphorus compound that serves as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key reagent for the synthesis of α,β-unsaturated carbonyl compounds and other complex molecules via the Horner-Wadsworth-Emmons (HWE) olefination reaction. This high-purity intermediate is essential for research and development laboratories, pharmaceutical manufacturers, and agrochemical producers seeking to create novel active ingredients and fine chemicals with precision and efficiency.

Application

• Pharmaceutical Intermediate: A crucial reagent in the synthesis of complex drug molecules, particularly those containing alkene functionalities, via the Horner-Wadsworth-Emmons reaction.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific phosphonate-based intermediates.
• Material Science: Employed in the development of specialty polymers, flame retardants, and ligands for metal catalysis.
• Organic Synthesis & Research: A fundamental building block in academic and industrial R&D for constructing carbon-carbon double bonds with high stereoselectivity.
• Flavor & Fragrance Industry: Used in the synthesis of specific aroma chemicals and flavoring agents.

Basic Information

Product Name	Diethyl (Methoxymethyl)Phosphonate
CAS No.	32806-04-5
Molecular Formula	C6H15O4P
Molecular Weight	182.16 g/mol
Synonyms	(Methoxymethyl)phosphonic Acid Diethyl Ester; Diethyl Methoxymethylphosphonate; Diethyl P,P-Bis(methoxymethyl)phosphonate (related); Methoxymethanephosphonic Acid Diethyl Ester; Phosphonic Acid, (Methoxymethyl)-, Diethyl Ester; HWE Reagent; Horner-Wadsworth-Emmons Reagent
EINECS	251-254-9

Quality Control

Our Diethyl (Methoxymethyl)Phosphonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific customer requirements, including research and commercial grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.425 - 1.435
Density (20°C)	1.08 - 1.12 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.