Description

1,7,7-Trimethylbicyclo[2.2.1]heptan-2-amine hydrochloride is a high-purity organic salt derivative of a substituted norbornane amine, valued for its role as a versatile chiral building block and intermediate in advanced synthesis. This compound is critical for research and development in fine chemical and pharmaceutical manufacturing, where precise molecular architecture is required. It is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel therapeutic compounds, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its rigid bicyclic structure for enhanced biological activity and selectivity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require a defined stereochemical center.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, including novel ring-opening and functionalization reactions.
• Material Science: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties derived from its bulky, rigid backbone.

Basic Information

Product Name	1,7,7-Trimethylbicyclo[2.2.1]heptan-2-amine hydrochloride
CAS No.	32768-19-7
Molecular Formula	C10H20ClN
Molecular Weight	189.72 g/mol
Synonyms	2-Aminobornane hydrochloride; 2-Bornylamine hydrochloride; 1,7,7-Trimethylbicyclo[2.2.1]heptan-2-amine HCl; endo-2-Bornylamine hydrochloride; Bicyclo[2.2.1]heptan-2-amine, 1,7,7-trimethyl-, hydrochloride; DL-Bornylamine hydrochloride; Bornan-2-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1,7,7-Trimethylbicyclo[2.2.1]heptan-2-amine hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (specify enantiomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.