Description

n-Hexane-1,1,1,6,6,6-D6 is a deuterated isotopologue of n-hexane, where six hydrogen atoms are replaced by deuterium atoms at specific terminal methyl positions. This high isotopic purity is critical for applications requiring a non-interfering internal standard or a solvent that minimizes proton signal interference in sensitive analytical techniques. It is an essential material for researchers and quality control laboratories in the pharmaceutical, chemical, and academic sectors who require precise spectroscopic and chromatographic analysis.

Application

• NMR Spectroscopy: Used extensively as an internal standard or deuterated solvent in Nuclear Magnetic Resonance (NMR) analysis to provide a lock signal and minimize background proton interference.
• Mass Spectrometry (MS): Serves as a valuable internal standard for quantitative analysis via Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS), improving accuracy.
• Chemical Reaction Studies: Employed as a deuterated reagent in mechanistic studies and kinetic isotope effect (KIE) experiments to trace reaction pathways.
• Pharmaceutical Research: Utilized in the synthesis and analysis of deuterated drug compounds and metabolites for enhanced metabolic stability and bioavailability studies.
• Analytical Reference Standard: Acts as a high-purity certified reference material (CRM) for calibrating instruments and validating analytical methods.
• Polymer Science: Used in the analysis of polymer structures and dynamics via NMR techniques.

Basic Information

Product Name	n-Hexane-1,1,1,6,6,6-D6
CAS No.	32740-20-8
Molecular Formula	C6D6H6
Molecular Weight	90.20 g/mol
Synonyms	Hexane-d6; Perdeuteriohexane; Deuterated Hexane; n-Hexane-d6; [2H6]Hexane; 1,1,1,6,6,6-Hexadeuteriohexane; Hexane-1,1,1,6,6,6-d6
EINECS	Contact for details

Quality Control

Every batch of n-Hexane-1,1,1,6,6,6-D6 is produced and tested under stringent quality management protocols to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including NMR and GC analysis, to ensure compliance with industry standards for deuterated solvents. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and specific tests are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong oxidizers. Due to its highly volatile nature, ensure containers are kept tightly sealed to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C (36-46°F) for extended stability, although room temperature (15-25°C) is acceptable for short-term use.

Specification

Item	Specification
Appearance	Colorless Clear Liquid
Identification (IR)	Conforms
Isotopic Enrichment (D)	≥ 99.0 atom % D
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.05%
NMR Solubility	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.