Description

1-O,2-O,3-O,4-o-Tetrakis(Trimethylsilyl)-6-Deoxy-β-L-Galactopyranose CAS NO 32727-31-4 is a highly functionalized, fully protected monosaccharide derivative, serving as a critical advanced intermediate in complex organic synthesis. Its value lies in providing a pre-silylated, deoxygenated galactose scaffold, which streamlines multi-step synthetic routes by eliminating repetitive protection and deprotection sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of nucleoside analogs, carbohydrate-based drugs, and sophisticated chiral building blocks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry: Serves as a protected precursor for the preparation of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Chiral Pool Synthesis: Utilized as a versatile chiral template for constructing enantiomerically pure natural products and active pharmaceutical ingredients (APIs).
• Glycobiology Research: Used in studies investigating carbohydrate-protein interactions, enzyme mechanisms, and metabolic pathways.
• Process Chemistry: Enables more efficient and scalable synthetic routes in fine chemical and API manufacturing due to its stability and handling properties.
• Diagnostic Reagent Development: Potential intermediate in creating labeled sugars or probes for imaging and diagnostic assays.

Basic Information

Item	Details
Product Name	1-O,2-O,3-O,4-o-Tetrakis(Trimethylsilyl)-6-Deoxy-β-L-Galactopyranose
CAS No.	32727-31-4
Molecular Formula	C18H44O5Si4
Molecular Weight	476.90 g/mol
Synonyms	6-Deoxy-1,2,3,4-tetra-O-trimethylsilyl-β-L-galactopyranose; 6-Deoxy-β-L-galactopyranose 1,2,3,4-tetrakis(trimethylsilyl) ether; β-L-6-Deoxygalactose tetrakis(trimethylsilyl) ether; Tetrakis-O-(trimethylsilyl)-6-deoxy-β-L-galactopyranose; Per-O-trimethylsilylated 6-deoxy-β-L-galactose; TMS-protected 6-deoxy-β-L-galactose; 32727-31-4
EINECS	Contact for details

Quality Control

Every batch of 1-O,2-O,3-O,4-o-Tetrakis(Trimethylsilyl)-6-Deoxy-β-L-Galactopyranose is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. We employ advanced analytical techniques including NMR (¹H, ¹³C), HPLC, and GC-MS for comprehensive characterization and purity verification. A detailed Certificate of Analysis (COA) with full spectral data and chromatograms is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.