Description

1-(2-Amino-4-Methylthiazol-5-Yl)-2-Bromoethanone is a high-purity brominated thiazole derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key electrophilic intermediate, enabling the construction of complex heterocyclic scaffolds with precision. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients, particularly in therapeutic areas requiring thiazole-based molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in developing advanced fungicides and herbicides, leveraging the bioactivity of the thiazole moiety.
• Chemical Biology Probes: Serves as a reactive handle for labeling or modifying biomolecules in proteomics and diagnostic assay development.
• Material Science: Employed in the synthesis of specialized polymers and organic electronic materials requiring specific heterocyclic units.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	1-(2-Amino-4-Methylthiazol-5-Yl)-2-Bromoethanone
CAS No.	32519-72-5
Molecular Formula	C6H7BrN2OS
Molecular Weight	235.10 g/mol
Synonyms	2-Bromo-1-(2-amino-4-methyl-1,3-thiazol-5-yl)ethanone; 5-Acetyl-4-methylthiazol-2-amine, 2-bromo derivative; 2-Bromo-1-(2-amino-4-methylthiazol-5-yl)ethan-1-one; α-Bromo-2-amino-4-methyl-5-thiazole ketone; 5-(2-Bromoacetyl)-4-methylthiazol-2-amine; Bromoacetylaminomethylthiazole (variation); Amino-methylthiazolyl bromoethanone
EINECS	Contact for details

Quality Control

Our 1-(2-Amino-4-Methylthiazol-5-Yl)-2-Bromoethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.