Description

Thiophene, 2,5-Dibromo-3-Fluoro- is a halogenated thiophene derivative, a versatile and high-value building block in advanced organic synthesis. Its precise substitution pattern makes it a critical intermediate for constructing complex molecular architectures with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorine-containing drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and metabolic stability.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed to create specialized ligands for transition metal catalysis, enabling more efficient and selective cross-coupling reactions.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and constructing complex heterocyclic systems in academic and industrial R&D settings.
• Liquid Crystal and Advanced Material Synthesis: Used as a core component in the design of fluorinated liquid crystals and other high-performance specialty materials.

Basic Information

Product Name	Thiophene, 2,5-Dibromo-3-Fluoro-
CAS No.	32431-85-9
Molecular Formula	C4HBr2FS
Molecular Weight	259.92 g/mol
Synonyms	2,5-Dibromo-3-fluorothiophene; 3-Fluoro-2,5-dibromothiophene; 2,5-Dibromo-3-fluoro-thiophene; Thiophene, 3-fluoro-2,5-dibromo-; 2,5-Dibromo-3-fluorothiofuran; 3-Fluor-2,5-dibromthiophen (German); 3-Fluoro-2,5-dibromothiophène (French)
EINECS	Contact for details

Quality Control

Our Thiophene, 2,5-Dibromo-3-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.