Description

3-Fluorothiophene-2-Carbaldehyde is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive aldehyde group and a fluorine-substituted thiophene ring, enabling precise molecular modifications. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require high-purity intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent for creating specialized polymers and organic electronic materials with tailored properties.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important substrate for investigating new fluorination reactions and understanding structure-activity relationships (SAR).
• Fine Chemical Production: Acts as a building block for synthesizing complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	3-Fluorothiophene-2-Carbaldehyde
CAS No.	32431-83-7
Molecular Formula	C5H3FOS
Molecular Weight	130.14 g/mol
Synonyms	2-Formyl-3-fluorothiophene; 3-Fluoro-2-thiophenecarboxaldehyde; 3-Fluoro-2-thiophenecarbaldehyde; 3-Fluorothiophene-2-carboxaldehyde; 3-Fluorothiophene-2-aldehyde; 3-Fluoro-2-formylthiophene; 3-Fluorothienyl-2-carbaldehyde; 2-Thiophenecarboxaldehyde, 3-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Fluorothiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.