Description

4-Fluorothiophene-2-Carbonitrile is a high-value fluorinated heterocyclic building block, specifically a thiophene derivative. This compound is essential for advanced organic synthesis, offering a versatile nitrile group and a fluorine atom for precise molecular modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science Precursor: Serves as a building block for functional polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorination reactions and heterocyclic chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for clients.

Basic Information

Product Name	4-Fluorothiophene-2-Carbonitrile
CAS No.	32431-77-9
Molecular Formula	C5H2FNS
Molecular Weight	127.14 g/mol
Synonyms	2-Cyano-4-fluorothiophene; 4-Fluoro-2-thiophenecarbonitrile; 4-Fluorothiophene-2-carbonitrile; 2-Thiophenecarbonitrile, 4-fluoro-; 4-Fluoro-thiophene-2-carbonitrile; 4-Fluorothienyl-2-carbonitrile; 4-Fluoro-2-cyanothiophene
EINECS	Contact for details

Quality Control

Our 4-Fluorothiophene-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.