Description

2-Thiophenecarboxylic Acid, 4-Fluoro- is a high-purity fluorinated heterocyclic building block of significant commercial and research interest. This compound is valued for its role as a key synthon in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom and thiophene ring enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of conductive polymers, organic semiconductors, and liquid crystals for electronic applications.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the exploration of new fluorination reactions and heterocyclic chemistry.
• Ligand and Catalyst Design: The carboxylic acid functionality allows for coordination to metal centers, making it useful for creating specialized ligands in catalytic systems.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 4-Fluoro-
CAS No.	32431-72-4
Molecular Formula	C5H3FO2S
Molecular Weight	146.14 g/mol
Synonyms	4-Fluorothiophene-2-carboxylic Acid; 4-Fluoro-2-thiophenecarboxylic Acid; 4-Fluorothiophene-2-carboxylic Acid; 4-Fluoro-2-thiophenic Acid; 4-Fluorothiophene-2-carboxylic acid; 4-Fluoro-2-thiophenecarboxylic acid; 4-Fluorothiophene-2-carboxylic acid; 4-Fluoro-2-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylic Acid, 4-Fluoro- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.