Description

2-(3-Chloropropanoyl)-1,2-Dihydroisoquinoline-1-Carbonitrile is a versatile and high-value synthetic intermediate characterized by its reactive chloropropanoyl and nitrile functional groups. This compound is critical for facilitating complex molecular transformations in advanced organic synthesis, offering a strategic building block for constructing intricate heterocyclic frameworks. It is primarily sought by research and development chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds with potential biological activity, serving as a core scaffold for drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its structural motifs can contribute to new modes of action.
• Fine Chemical Production: Employed as a specialized building block for the manufacture of advanced materials, dyes, and other performance chemicals.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in cyclization and annulation reactions.
• Chemical Library Development: Serves as a starting material for generating diverse compound libraries for high-throughput screening in life sciences.

Basic Information

Product Name	2-(3-Chloropropanoyl)-1,2-Dihydroisoquinoline-1-Carbonitrile
CAS No.	32409-95-3
Molecular Formula	C13H11ClN2O
Molecular Weight	246.69 g/mol
Synonyms	1,2-Dihydro-2-(3-chloro-1-oxopropyl)isoquinoline-1-carbonitrile; 3-Chloro-1-(1-cyano-1,2-dihydroisoquinolin-2-yl)-1-propanone; 2-(3-Chloropropionyl)-1,2-dihydroisoquinoline-1-carbonitrile; 1-Cyano-2-(3-chloropropionyl)-1,2-dihydroisoquinoline; 32409-95-3; 2-(3-Chloropropanoyl)-1-cyano-1,2-dihydroisoquinoline
EINECS	Contact for details

Quality Control

Our 2-(3-Chloropropanoyl)-1,2-Dihydroisoquinoline-1-Carbonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.