Description

8,14-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylmorphinan-6α-Ol Acetate is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex morphinan structure makes it a critical precursor for the synthesis of specialized opioid receptor ligands and other bioactive molecules. This compound is essential for research institutions and pharmaceutical companies focused on neuropharmacology, medicinal chemistry, and the development of novel analgesic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent opioid analgesics and antagonists for clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new central nervous system (CNS) active compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical testing laboratories.
• Biochemical Research: Employed in studies investigating opioid receptor binding, signal transduction pathways, and neurochemical mechanisms.
• Process Development: Utilized in the scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	8,14-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylmorphinan-6α-Ol Acetate
CAS No.	32404-16-3
Molecular Formula	C21H23NO4
Molecular Weight	353.41 g/mol
Synonyms	6α-Acetoxy-8,14-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan; 6α-Acetoxydihydrothebaine; 6α-Acetoxy-8,14-dihydrothebaine; 8,14-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol acetate; Dihydrothebaine-6α-acetate; Thebaine derivative acetate; 6-Acetoxy-8,14-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan
EINECS	Contact for details

Quality Control

Our 8,14-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylmorphinan-6α-Ol Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.