Description

1β,3α-Bis(Trimethylsilyloxy)Cyclohexane is a specialized organosilicon compound, recognized for its role as a versatile silylating agent and protected intermediate in advanced organic synthesis. Its value lies in providing efficient protection for hydroxyl groups, enabling complex multi-step reactions in sensitive chemical environments. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly where selective hydroxyl protection is required.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require specific stereochemistry.
• Fine Chemical Production: Serves as a protected synthon for creating fragrances, flavors, and specialty performance chemicals.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and catalysis studies.
• Material Science: Potential precursor in the development of silicon-containing polymers and hybrid materials.
• Process Chemistry: Enables scalable, robust synthetic routes in pilot plant and manufacturing settings.

Basic Information

Product Name	1β,3α-Bis(Trimethylsilyloxy)Cyclohexane
CAS No.	32282-77-2
Molecular Formula	C12H28O2Si2
Molecular Weight	260.53 g/mol
Synonyms	Cyclohexane, 1,3-bis[(trimethylsilyl)oxy]-, (1R,3S)-rel-; (1R,3S)-1,3-Bis(trimethylsilyloxy)cyclohexane; 1,3-Bis-O-(trimethylsilyl)cyclohexane-1,3-diol; 1β,3α-Di-O-trimethylsilyl-cyclohexane-1,3-diol; TMS-protected cyclohexane-1,3-diol; 1,3-Cyclohexanediol bis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our 1β,3α-Bis(Trimethylsilyloxy)Cyclohexane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Purity (GC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.