Description

Methyl Acetate-D6 is a deuterated isotopologue of methyl acetate, where all six hydrogen atoms are replaced by deuterium. This high isotopic purity makes it an essential standard and reagent in advanced analytical chemistry and spectroscopic studies. It is primarily used by researchers and quality control laboratories in the pharmaceutical, agrochemical, and academic sectors for applications requiring precise internal standards or non-interfering solvents in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS).

Application

• NMR Spectroscopy Solvent & Internal Standard: Serves as a deuterated solvent for proton NMR, providing a lock signal and a chemical shift reference without background interference.
• Mass Spectrometry (MS): Used as a reagent or matrix in MS analyses, including GC-MS and LC-MS, for method development and quantitative analysis.
• Pharmaceutical Research & Metabolism Studies: Acts as a stable-isotope labeled tracer or internal standard in drug metabolism and pharmacokinetics (DMPK) research.
• Chemical Synthesis Intermediate: Employed in specialized synthetic pathways where deuterium incorporation is required for creating labeled target molecules.
• Analytical Method Development & Validation: Critical for developing and validating sensitive analytical methods that require high-purity deuterated compounds.
• Quality Control & Reference Material: Used as a certified reference material (CRM) to calibrate instruments and ensure accuracy in analytical laboratories.

Basic Information

Product Name	Methyl Acetate-D6
CAS No.	32113-85-2
Molecular Formula	C2H3D3OCOCD3 or C3D6O2
Molecular Weight	64.12 g/mol (theoretical)
Synonyms	Acetic Acid-d3 Methyl-d3 Ester; Methyl-d3 Acetate-d3; Deuterated Methyl Acetate; [2H6]Methyl Acetate; Methyl Acetate-d6; Perdeuterated Methyl Acetate; Methyl Acetate (Hexadeuterated)
EINECS	Contact for details

Quality Control

Our Methyl Acetate-D6 is produced and handled under strict quality protocols to ensure the highest isotopic and chemical purity for research applications. Each batch is analyzed using advanced techniques including NMR and GC-MS to confirm deuterium enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., D atom %), chemical assay, and solvent residue is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-8°C to maintain long-term stability and minimize evaporation loss.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (D atom %)	≥ 99.0% (or as specified)
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.