Description

Isopropyl 2-Aminothiophene-3-Carboxylate (Saltdata: Free) is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thiophene-based drug candidates, including potential kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and dyes due to its electron-rich thiophene core.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for further functionalization to create diverse chemical libraries.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Isopropyl 2-Aminothiophene-3-Carboxylate (Saltdata: Free)
CAS No.	31891-08-4
Molecular Formula	C8H11NO2S
Molecular Weight	185.24 g/mol
Synonyms	2-Amino-3-isopropoxycarbonylthiophene; Isopropyl 2-amino-3-thiophenecarboxylate; 2-Aminothiophene-3-carboxylic acid isopropyl ester; 3-Carboxy-2-aminothiophene isopropyl ester; 31891-08-4; 2-Amino-3-(isopropoxycarbonyl)thiophene; Isopropyl α-aminothiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Isopropyl 2-Aminothiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.