Description

Ethyl 2-Aminothiophene-3-Carboxylate is a versatile heterocyclic building block of significant importance in synthetic organic chemistry. Its core value lies in its bifunctional structure, featuring both an amine and an ester group on a thiophene scaffold, making it a key precursor for the synthesis of complex pharmacologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial starting material for the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety's bioactivity.
• Material Science Precursor: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials due to the thiophene ring's conductive properties.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and organic pigments.
• Chemical Research & Development: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new heterocyclic chemistry.
• Custom Synthesis: A foundational substrate for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	Ethyl 2-Aminothiophene-3-Carboxylate
CAS No.	31891-06-2
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	2-Amino-3-(ethoxycarbonyl)thiophene; Ethyl 2-Amino-3-thiophenecarboxylate; 3-Carbethoxy-2-aminothiophene; 2-Aminothiophene-3-carboxylic acid ethyl ester; 2-Amino-3-carbethoxythiophene; 3-Thiophenecarboxylic acid, 2-amino-, ethyl ester; Ethyl α-aminothiophene-β-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Aminothiophene-3-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.