Description

3-(3-Carboxypropionylamino)Phenylboronic Acid is a specialized boronic acid derivative featuring both a carboxylic acid and a boronic acid functional group on an aromatic scaffold. This unique bifunctional structure makes it a valuable building block and coupling agent in advanced organic synthesis, particularly for creating complex molecules via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and material scientists for the synthesis of active pharmaceutical ingredients (APIs), functional polymers, and novel chemical probes.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, especially those requiring biaryl linkages common in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that incorporate phenylboronic acid motifs.
• Material Science: Serves as a monomer or cross-linking agent in the development of boronate ester-based polymers, hydrogels, and sensors with responsive properties.
• Bioconjugation & Probe Development: Utilized for labeling biomolecules or creating chemical probes that leverage the boronic acid group's affinity for diols, such as sugars.
• Organic Synthesis Reagent: Acts as a versatile coupling partner in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating libraries of compounds for screening.

Basic Information

Product Name	3-(3-Carboxypropionylamino)Phenylboronic Acid
CAS No.	31754-00-4
Molecular Formula	C10H12BNO5
Molecular Weight	237.02 g/mol
Synonyms	3-(3-Carboxypropionamido)benzeneboronic acid; [3-[(3-Carboxypropionyl)amino]phenyl]boronic acid; 3-(3-Carboxypropionylamino)benzeneboronic acid; 3-Carboxypropionamidophenylboronic Acid; B-[3-[(3-Carboxy-1-oxopropyl)amino]phenyl]boronic acid; 3-[(3-Carboxypropanoyl)amino]phenylboronic acid; 31754-00-4; 3-CPAPBA
EINECS	Contact for details

Quality Control

Our 3-(3-Carboxypropionylamino)Phenylboronic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance as a synthetic building block. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.