Description

(-)-Bromochlorofluoromethane is a chiral halogenated methane derivative, specifically the levorotatory enantiomer, with the CAS registry number 31747-37-2. This compound is valued as a specialized building block and reagent in advanced synthetic chemistry, particularly for introducing chiral centers and fluorinated motifs. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, enantiomerically defined intermediates for stereoselective synthesis and molecular design.

Application

• Pharmaceutical Intermediate: Serves as a chiral synthon in the stereoselective synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated groups.
• Agrochemical Research: Used in developing novel, enantiomerically pure pesticides and herbicides where specific stereochemistry impacts biological activity.
• Advanced Material Synthesis: Acts as a precursor for fluorinated polymers and liquid crystals, where the chiral center can influence material properties.
• Asymmetric Catalysis: Employed as a reagent or ligand precursor in catalytic reactions to control stereochemical outcomes.
• Reference Standard: Used as an analytical standard in chiral chromatography and spectroscopy for method development and quality control.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution and coupling reactions to construct complex, halogenated molecular architectures.

Basic Information

Product Name	(-)-Bromochlorofluoromethane
CAS No.	31747-37-2
Molecular Formula	CHBrClF
Molecular Weight	147.37 g/mol
Synonyms	(-)-Bromochloromonofluoromethane; (S)-Bromochlorofluoromethane; Levo-Bromochlorofluoromethane; (1S)-Bromochlorofluoromethane; Bromochlorofluoromethane, (-)-; FC-31B1 (enantiomer); Halon 1011 (enantiomer); Methane, bromochlorofluoro-, (S)-
EINECS	Contact for details

Quality Control

Our (-)-Bromochlorofluoromethane is produced under controlled conditions to ensure high enantiomeric purity and chemical consistency. Each batch undergoes rigorous analytical testing, including chiral GC/HPLC, NMR, and specific rotation measurement, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area, ideally at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use to prevent loss and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.