Description

1-Phenylcyclopropanemethanol is a versatile chiral building block featuring a cyclopropane ring fused with a phenyl-substituted methanol group. This compound matters for its unique structural rigidity and stereochemistry, which are critical for modulating the biological activity and physicochemical properties of advanced pharmaceutical intermediates. Industries involved in the research and synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals will find this compound highly valuable.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the cyclopropane moiety can enhance stability and efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of advanced organic materials and liquid crystals due to its rigid molecular structure.
• Flavor and Fragrance Industry: Potential intermediate for creating complex aroma chemicals with unique olfactory properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-Phenylcyclopropanemethanol
CAS No.	31729-66-5
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	(1-Phenylcyclopropyl)methanol; α-(Cyclopropyl)benzenemethanol; Benzenemethanol, α-cyclopropyl-; Cyclopropanemethanol, 1-phenyl-; 1-Phenylcyclopropylcarbinol; (1-Phenyl-cyclopropyl)-methanol
EINECS	Contact for details

Quality Control

Our 1-Phenylcyclopropanemethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (Specific enantiomer available)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.