Description

N,n-Dimethyl-D6-Acetamide is a deuterated isotopologue of the common polar aprotic solvent N,N-Dimethylacetamide (DMAc), where six hydrogen atoms are replaced by deuterium. This deuteration makes it an invaluable tool for nuclear magnetic resonance (NMR) spectroscopy, providing a non-interfering, deuterated solvent for analyzing compounds in deuterium-depleted environments. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity deuterated solvents for precise spectroscopic analysis and reaction studies.

Application

• NMR Spectroscopy Solvent: Primary application as a deuterated solvent for proton (1H) and carbon-13 (13C) NMR analysis, offering minimal background interference.
• Pharmaceutical Research & Development: Used in the synthesis and analysis of deuterated drug molecules and active pharmaceutical ingredients (APIs) for metabolic studies.
• Chemical Reaction Medium: Serves as a deuterated reaction solvent in specialized organic synthesis, particularly where kinetic isotope effects are studied.
• Polymer Science: Employed in the analysis and processing of polymers and high-performance fibers where DMAc is a standard solvent.
• Academia & Analytical Laboratories: Critical reagent for university research, contract research organizations (CROs), and analytical service providers.
• Quality Control & Reference Standards: Used in the preparation of internal standards and for method validation in regulated laboratory environments.

Basic Information

Product Name	N,n-Dimethyl-D6-Acetamide
CAS No.	31591-08-9
Molecular Formula	C4D6H3NO
Molecular Weight	91.14 g/mol
Synonyms	N,N-Dimethylacetamide-d6; DMAc-d6; Deuterated N,N-Dimethylacetamide; Acetamide-d6, N,N-dimethyl-; (Trideuteroacetyl)(dimethyl)amine-d3; Dimethyl-d6-acetamide; Perdeuterated DMAc; Hexadeuterio-N,N-dimethylacetamide
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-D6-Acetamide is produced and tested to meet the exacting standards required for analytical and research applications. Each batch undergoes rigorous analysis, including NMR spectroscopy for deuterium enrichment and purity, gas chromatography (GC) for solvent impurities, and Karl Fischer titration for water content. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (typically >99.5 atom % D), chemical purity, and specific tests is provided with every shipment to ensure traceability and compliance with your laboratory's quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Deuterium Content (NMR)	>99.5 atom % D
Purity (GC)	>99.5%
Water Content (KF)	<0.1%
Residue on Evaporation	<0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.