Description

1-Azabicyclo[2.2.2]oct-2-ene-3-carboxylic acid methyl ester is a versatile bicyclic tertiary amine and ester derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its unique, rigid scaffold is highly valued for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Ligand and Catalyst Precursor: Used in the development of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced pesticides and herbicides with specific activity profiles.
• Academic and R&D Research: Employed in universities and corporate labs for methodological studies and exploring new chemical spaces.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals and flavors/fragrances.

Basic Information

Product Name	1-Azabicyclo[2.2.2]oct-2-ene-3-carboxylic acid methyl ester
CAS No.	31539-88-5
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	Methyl 1-azabicyclo[2.2.2]oct-2-ene-3-carboxylate; 3-Quinuclidinecarboxylic acid, 2,3-didehydro-, methyl ester; Methyl 2,3-didehydro-3-quinuclidinecarboxylate; 1-Azabicyclo[2.2.2]oct-2-ene-3-carboxylic acid, methyl ester; 2,3-Dehydroquinuclidine-3-carboxylic acid methyl ester; Quinuclidine derivative intermediate
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]oct-2-ene-3-carboxylic acid methyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.