Description

N-(p-Toluenesulfonyl)Indole is a versatile sulfonamide-protected indole derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a protected indole building block, enabling selective functionalization for the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based drug candidates, including potential kinase inhibitors and serotonin receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides that leverage the indole scaffold for biological activity.
• Organic Synthesis Reagent: Acts as a protected indole precursor in multi-step synthetic routes, allowing for reactions on other parts of the molecule without affecting the indole nitrogen.
• Material Science Research: Employed in the development of organic electronic materials and functional dyes where the indole-sulfonamide structure contributes to specific photophysical properties.
• Academic & R&D: A standard reagent in university and industrial research laboratories for methodological development and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	N-(p-Toluenesulfonyl)Indole
CAS No.	31271-90-6
Molecular Formula	C15H13NO2S
Molecular Weight	271.33 g/mol
Synonyms	1H-Indole, 1-[(4-methylphenyl)sulfonyl]-; 1-Tosylindole; N-Tosylindole; 1-(4-Methylphenylsulfonyl)indole; 1-(p-Tolylsulfonyl)indole; N-(4-Methylbenzenesulfonyl)indole; p-Toluenesulfonylindole; Tosyl Indole
EINECS	Contact for details

Quality Control

Our N-(p-Toluenesulfonyl)Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP and ISO guidelines for consistent, reliable material supply to the fine chemical and pharmaceutical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.