Description

Dehydroaltenusin is a specialized natural product derivative with significant biological activity. This compound is valued for its role as a potent and selective inhibitor of DNA polymerase, making it a critical tool in biochemical research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral, anticancer, and enzyme mechanism studies. Our supply ensures high purity and batch-to-batch consistency to meet the stringent demands of advanced life science applications.

Application

• Biochemical Research: Used as a specific inhibitor in studies of DNA polymerase α and ε to elucidate enzyme mechanisms and functions.
• Antiviral Drug Discovery: Serves as a lead compound or reference standard in the development of novel antiviral agents targeting viral replication.
• Oncology Research: Investigated for its potential anti-proliferative effects in cancer cell line studies and as a tool for understanding DNA replication in malignancies.
• Enzyme Profiling: Employed in high-throughput screening assays to identify and characterize new polymerase inhibitors.
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Academic Research: A key reagent for universities and institutes conducting fundamental research in molecular biology and genetics.

Basic Information

Product Name	Dehydroaltenusin
CAS No.	31186-13-7
Molecular Formula	C20H16O7
Molecular Weight	368.34 g/mol
Synonyms	(-)-Dehydroaltenusin; NSC 348900; 6-Hydroxy-3,4',5,7-tetramethoxyflavone; 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one derivative; Altenusin derivative; DNA Polymerase Inhibitor; Polyporic acid derivative
EINECS	Contact for details

Quality Control

Every batch of Dehydroaltenusin is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and strength, compliant with research-grade material standards. A detailed Certificate of Analysis (COA) including results for HPLC purity, NMR identification, and residual solvent analysis is supplied with each shipment to guarantee reproducible and reliable performance in your applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.