Description

Isoquinoline, 8-Fluoro-1-Methyl- CAS NO 31181-27-8 is a high-purity fluorinated isoquinoline derivative, a key building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both fluorine and methyl substituents to the isoquinoline core, enabling precise modulation of electronic and steric properties in target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly in developing molecules for central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used to construct novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity, metabolic stability, and lipophilicity.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and fluorescent dyes due to its rigid, aromatic structure.
• Chemical Synthesis: Employed in academic and industrial research for method development, such as cross-coupling reactions and fluorination studies.
• Ligand Synthesis: Useful for preparing complexing agents and catalysts in asymmetric synthesis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Isoquinoline, 8-Fluoro-1-Methyl-
CAS No.	31181-27-8
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	8-Fluoro-1-methylisoquinoline; 1-Methyl-8-fluoroisoquinoline; 8-Fluoro-1-methyl-isoquinoline; 31181-27-8; 8-Fluoro-1-methyl-isoquinoline; 8-Fluoro-1-methyl-isoquinoline; 1-Methyl-8-fluoroisoquinoline
EINECS	Contact for details

Quality Control

Our Isoquinoline, 8-Fluoro-1-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.