Description

Carbamoylphosphonic Acid Diethyl Ester is a versatile organophosphorus compound with a unique carbamoylphosphonate structure. This chemical serves as a valuable synthetic intermediate and ligand in advanced chemical synthesis and materials science. It is particularly relevant for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting bone metabolism or requiring phosphonate bioisosteres.
• Agrochemical Research: Used in the development of new herbicides, plant growth regulators, and fungicides with unique modes of action.
• Coordination Chemistry & Catalysis: Acts as a chelating ligand for metal ions, useful in creating catalysts for organic transformations or in materials for metal sequestration.
• Chemical Biology Probe: Employed in the study of enzymatic processes, particularly those involving phosphate or pyrophosphate analogues.
• Material Science Precursor: Serves as a monomer or additive in the synthesis of specialty polymers and functional materials.
• Organic Synthesis Reagent: Utilized in Horner-Wadsworth-Emmons (HWE) and related olefination reactions to construct complex organic molecules.

Basic Information

Product Name	Carbamoylphosphonic Acid Diethyl Ester
CAS No.	31142-29-7
Molecular Formula	C5H12NO4P
Molecular Weight	181.13 g/mol
Synonyms	Diethyl (aminocarbonyl)phosphonate; Diethyl carbamoylphosphonate; Diethyl phosphoramidate; (Aminocarbonyl)phosphonic Acid Diethyl Ester; Carbamoylphosphonate Diethyl Ester; Phosphoramidic Acid, N-(Diethoxyphosphinyl)-; NSC 163063; EINECS 250-485-6
EINECS	250-485-6

Quality Control

Our Carbamoylphosphonic Acid Diethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay, impurity profile, and physical characteristics. Our quality systems support compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Impurity A	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.