Description

Pyrimidine, 2,4,6-Tris[(Trimethylsilyl)Oxy]- is a specialized organosilicon-protected derivative of pyrimidine, a fundamental heterocyclic compound. This compound is a critical synthetic intermediate, valued for its role in protecting reactive hydroxyl groups during complex organic synthesis, thereby enabling the construction of sensitive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional compounds. Its unique structure offers precise control in multi-step chemical processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs) requiring selective hydroxyl protection.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where sensitive functional groups must be preserved.
• Organic Synthesis Reagent: Serves as a versatile protecting group agent in academic and industrial laboratories for complex multi-step organic transformations.
• Material Science Research: Potential precursor in the development of silicon-containing polymers or hybrid organic-inorganic materials with tailored properties.
• Chemical Derivatization: Employed in analytical chemistry to derivative compounds for gas chromatography (GC) or mass spectrometry (MS) analysis by introducing volatile trimethylsilyl groups.

Basic Information

Product Name	Pyrimidine, 2,4,6-Tris[(Trimethylsilyl)Oxy]-
CAS No.	31111-39-4
Molecular Formula	C15H33N2O3Si3
Molecular Weight	389.70 g/mol
Synonyms	2,4,6-Tris(trimethylsiloxy)pyrimidine; 2,4,6-Tris(trimethylsilyloxy)pyrimidine; Pyrimidine-2,4,6-triol tris(trimethylsilyl) ether; 2,4,6-Trihydroxypyrimidine tris(trimethylsilyl) ether; 2,4,6-Tri-O-(trimethylsilyl)pyrimidine; TMS-protected pyrimidinetriol; Hexamethyl[2,4,6-pyrimidinetriyltris(oxy)]trisilane
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2,4,6-Tris[(Trimethylsilyl)Oxy]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance as a synthetic intermediate. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place (recommended 2-8°C for long-term stability). Allow the container to reach ambient temperature before opening to minimize moisture ingress and product loss.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.