Description

Tetrahydrothiophene-2,2,5,5-D4 is a deuterated analog of tetrahydrothiophene, a sulfur-containing heterocyclic compound. This stable isotope-labeled compound is essential for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, a tracer in metabolic studies, and a building block in the synthesis of labeled compounds.

Application

• Internal standard for Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) analysis.
• Tracer compound in metabolic pathway and pharmacokinetic studies within pharmaceutical R&D.
• Deuterated building block for the synthesis of more complex labeled pharmaceutical intermediates and active ingredients.
• Use in nuclear magnetic resonance (NMR) spectroscopy as a solvent or shift reference in specific experiments.
• Critical material for environmental fate studies and degradation pathway analysis of sulfur-containing chemicals.
• Research applications in mechanistic organic chemistry and reaction kinetics.

Basic Information

Product Name	Tetrahydrothiophene-2,2,5,5-D4
CAS No.	31081-24-0
Molecular Formula	C4H4D4S
Molecular Weight	92.19 g/mol
Synonyms	THT-d4; Tetrahydrothiophene-d4; [2,2,5,5-2H4]Tetrahydrothiophene; Perdeuterotetrahydrothiophene (partial); Thiophane-d4; Tetramethylene sulfide-d4; Deuterated tetrahydrothiophene; 2,2,5,5-Tetradeutero-thiolane
EINECS	Contact for details

Quality Control

Our Tetrahydrothiophene-2,2,5,5-D4 is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D atom %), chemical purity by GC or NMR, and residual solvent content. We adhere to relevant quality management standards to ensure batch-to-batch consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat and ignition sources. Due to its high volatility, ensure containers are kept tightly sealed when not in use. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.