Description

Phosphoric Acid, Bis(Trimethylsilyl) 2,3-Bis[(Trimethylsilyl)Oxy]Propy L Ester is a specialized organosilicon derivative of phosphoric acid, designed for advanced synthetic applications. This compound is valued for its role as a protected phosphate reagent and silylating agent, enabling precise chemical transformations under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key reagent for the introduction of protected phosphate groups in nucleoside, nucleotide, and prodrug development.
• Agrochemical Research: Employed in the synthesis of novel phosphate-containing pesticides and plant growth regulators.
• Chemical Derivatization: Acts as a potent silylating agent for analytical chemistry, protecting hydroxyl groups in gas chromatography (GC) and mass spectrometry (MS) sample preparation.
• Materials Science: Serves as a precursor or surface-modifying agent in the development of specialty silicones and phosphate-based functional materials.
• Process Chemistry: Facilitates specific phosphorylation steps in multi-step synthetic routes under controlled conditions.
• Laboratory Reagent: Used in research settings for mechanistic studies and the synthesis of sensitive organophosphorus compounds.

Basic Information

Product Name	Phosphoric Acid, Bis(Trimethylsilyl) 2,3-Bis[(Trimethylsilyl)Oxy]Propy L Ester
CAS No.	31038-11-6
Molecular Formula	C15H41O6PSi4
Molecular Weight	468.89 g/mol
Synonyms	1,2,3-Propanetriol, 1-(bis(trimethylsilyl) phosphoryl)-, 2,3-bis(trimethylsilyl) ether; Glycerol 1-(Bis(trimethylsilyl) phosphate) 2,3-Bis(trimethylsilyl) Ether; Tris(trimethylsilyl) Glycerolphosphate; TMS-Glycerol Phosphate; Silylated Glycerol Phosphate; Phosphoric Acid Tris(trimethylsilyl) Glycerol Ester; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of this high-purity synthetic intermediate is produced and analyzed under strict quality management protocols. Our products undergo rigorous testing, including HPLC, GC, NMR, and 31P-NMR analysis, to ensure identity, purity, and consistency for critical research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure (1H, 13C, 31P)
Assay (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.