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n-[[n-[(Benzyloxy)Carbonyl]-3-[1-(2,4-Dinitrophenyl)-1H-Imidazol-5-Yl]-L-Alanyl]Oxy]Succinimide CAS NO 31008-75-0


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CAS No.:31008-75-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[[n-[(Benzyloxy)Carbonyl]-3-[1-(2,4-Dinitrophenyl)-1H-Imidazol-5-Yl]-L-Alanyl]Oxy]Succinimide is a specialized, high-purity chemical building block primarily used in advanced organic synthesis. This compound is valued for its role as an activated ester intermediate, enabling efficient peptide coupling reactions under mild conditions. It is essential for researchers and process chemists in pharmaceutical development, agrochemical research, and advanced material science who require reliable, high-quality reagents for constructing complex molecular architectures.

Application

  • Peptide Synthesis: Serves as a key activated ester intermediate for the coupling of sterically hindered or sensitive amino acids in solid-phase and solution-phase peptide synthesis.
  • Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for constructing specific peptide-based drug candidates.
  • Bioconjugation: Facilitates the site-specific labeling and modification of proteins, antibodies, and other biomolecules for diagnostic and therapeutic applications.
  • Agrochemical Research: Employed in the synthesis of peptide-mimetic compounds for the development of new crop protection agents.
  • Chemical Biology Probes: Acts as a reagent for synthesizing activity-based probes and other tools to study enzyme function and biological pathways.
  • Material Science: Used in the preparation of functionalized polymers and dendrimers with precise chemical structures.

Basic Information

Product Name n-[[n-[(Benzyloxy)Carbonyl]-3-[1-(2,4-Dinitrophenyl)-1H-Imidazol-5-Yl]-L-Alanyl]Oxy]Succinimide
CAS No. 31008-75-0
Molecular Formula C24H20N6O9
Molecular Weight 536.45 g/mol
Synonyms N-[(Benzyloxy)carbonyl]-3-[1-(2,4-dinitrophenyl)-1H-imidazol-5-yl]-L-alanine N-hydroxysuccinimide ester; Z-Dnpim-Ala-OSu; Cbz-Dnpim-Ala-OSu; N-CBZ-3-(1-(2,4-Dinitrophenyl)-1H-imidazol-5-yl)-L-alanine N-succinimidyl ester; N-[(Benzyloxy)carbonyl]-3-[1-(2,4-dinitrophenyl)-1H-imidazol-5-yl]-L-alanyloxy]succinimide; Dnpim-containing peptide coupling reagent; CBZ-Dnpim-Alanine-OSu Ester
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Quality Control

Our n-[[n-[(Benzyloxy)Carbonyl]-3-[1-(2,4-Dinitrophenyl)-1H-Imidazol-5-Yl]-L-Alanyl]Oxy]Succinimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is moisture-sensitive and should be handled under dry conditions. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance Yellow to orange crystalline powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Solubility Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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