Description

Dimethyl Succinate-D4 is a high-purity, isotopically labeled derivative of dimethyl succinate, where four hydrogen atoms are replaced by deuterium. This compound is essential as a stable isotope-labeled internal standard for precise quantitative analysis in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It is primarily required by analytical laboratories, pharmaceutical researchers, and chemical manufacturers engaged in metabolic studies, quality control, and the synthesis of labeled compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of dimethyl succinate and related metabolites in complex biological and chemical matrices.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated solvent or a tracer in reaction mechanisms and structural elucidation studies.
• Pharmaceutical Research: Critical in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of active pharmaceutical ingredients.
• Chemical Synthesis: Employed as a labeled building block for the preparation of more complex deuterated organic compounds.
• Environmental & Food Analysis: Facilitates the detection and measurement of succinate esters and related compounds at trace levels.
• Biochemical Research: Used in metabolic pathway analysis, particularly in studies involving the citric acid cycle and related biochemistry.

Basic Information

Product Name	Dimethyl Succinate-D4
CAS No.	30994-23-1
Molecular Formula	C6D4H4O4
Molecular Weight	148.15 g/mol
Synonyms	Succinic Acid-d4 Dimethyl Ester; Dimethyl Butanedioate-d4; Butanedioic Acid-d4, Dimethyl Ester; Deuterated Dimethyl Succinate; [2H4]-Dimethyl Succinate; Methyl Succinate-d4; DMS-d4
EINECS	Contact for details

Quality Control

Our Dimethyl Succinate-D4 is produced and tested under stringent quality management systems to ensure exceptional isotopic and chemical purity for research applications. Each batch is characterized by advanced analytical techniques including GC-MS, NMR, and HPLC to confirm deuterium incorporation and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.