Description

(20S)-17,21-[(Butylboranediyl)Bisoxy]-3α,20-Dihydroxy-5β-Pregnan-11-One is a high-purity, synthetic steroid derivative with a unique boronic ester functionalization. This compound is valued as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents, particularly in the field of endocrinology. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel corticosteroid analogs and other steroidal drugs.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and hormone receptor research.
• Process Chemistry: Serves as a strategic intermediate in multi-step organic synthesis for producing target molecules with high stereochemical purity.
• Academic Research: Employed in university and institutional labs for investigating boronic acid chemistry in medicinal chemistry applications.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs developing client-specific bioactive compounds.

Basic Information

Product Name	(20S)-17,21-[(Butylboranediyl)Bisoxy]-3α,20-Dihydroxy-5β-Pregnan-11-One
CAS No.	30888-51-8
Molecular Formula	C₂₉H₄₇BO₅
Molecular Weight	486.50 g/mol
Synonyms	17,21-[(Butylboranediyl)bis(oxy)]-3α,20-dihydroxy-5β-pregnan-11-one, (20S)-; 5β-Pregnan-11-one, 17,21-[(butylboranediyl)bis(oxy)]-3α,20-dihydroxy-, (20S)-; Butylboronic acid cyclic ester with 3α,17,20,21-tetrahydroxy-5β-pregnan-11-one; 3α,20-Dihydroxy-17,21-(butylboranediylbisoxy)-5β-pregnan-11-one
EINECS	Contact for details

Quality Control

Our (20S)-17,21-[(Butylboranediyl)Bisoxy]-3α,20-Dihydroxy-5β-Pregnan-11-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a dry, cool place. Due to its hygroscopic and easily oxidized nature, the container must be sealed immediately after use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.