Description

(7As)-9-Ethyl-5,6,7,7Aα,8,8Aα,9,10-Octahydro-12β-Hydroxy-7-Methylindolo[3,2,1-Ij]Pyrano[3,4-B][1,5]Naphthyridine-12Aα(12H)-Carboxylic Acid Methyl Ester is a complex, high-purity organic compound belonging to the class of fused polycyclic alkaloids. This compound is of significant interest as a key advanced intermediate in the synthesis of novel pharmaceutical agents, particularly those targeting neurological and oncological pathways. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of new therapeutic molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex alkaloid-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new bioactive molecules.
• Process Chemistry Development: Serves as a reference standard and starting material for scaling up synthetic routes in API (Active Pharmaceutical Ingredient) manufacturing.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
• Biochemical Tool Compound: Potential use as a probe or inhibitor in biological assays to study specific enzyme or receptor interactions.

Basic Information

Item	Details
Product Name	(7As)-9-Ethyl-5,6,7,7Aα,8,8Aα,9,10-Octahydro-12β-Hydroxy-7-Methylindolo[3,2,1-Ij]Pyrano[3,4-B][1,5]Naphthyridine-12Aα(12H)-Carboxylic Acid Methyl Ester
CAS No.	30867-56-2
Molecular Formula	C23H28N2O4
Molecular Weight	396.48 g/mol
Synonyms	Methyl (7aα,12aα,12bβ)-9-Ethyl-12b-hydroxy-7-methyl-2,3,4,5,6,7,7a,8,12a,12b-decahydro-1H-indolo[3,2,1-ij]pyrano[3,4-b][1,5]naphthyridine-12a-carboxylate; 12b-Hydroxy-7-methyl-9-ethyl-2,3,4,5,6,7,7a,8,12a,12b-decahydro-1H-indolo[3,2,1-ij]pyrano[3,4-b][1,5]naphthyridine-12a-carboxylic acid methyl ester; Alkaloid C-23 Intermediate; Fused Indolo-Pyrano-Naphthyridine Derivative.
EINECS	Contact for details

Quality Control

Our (7As)-9-Ethyl-5,6,7,7Aα,8,8Aα,9,10-Octahydro-12β-Hydroxy-7-Methylindolo[3,2,1-Ij]Pyrano[3,4-B][1,5]Naphthyridine-12Aα(12H)-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.