Description

(7As,9E)-9-Ethylidene-5,6,7,7Aα,8,8Aα,9,10-Octahydro-12β-Acetoxy-7-Acetylindolo[3,2,1-Ij]Pyrano[3,4-B][1,5]Naphthyridine-12Aα(12H)-Carboxylic Acid Methyl Ester is a complex, high-purity organic compound belonging to the class of indole-fused polycyclic alkaloid derivatives. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought by R&D and process development teams in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Core scaffold for the design and development of new drug candidates targeting neurological and oncological pathways.
• Process Chemistry & Scale-Up: Used in route development and optimization for the commercial manufacturing of specialty pharmaceuticals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions.
• Biochemical Research: Investigated for its biological activity and potential as a tool compound in biochemical assays.

Basic Information

Product Name	(7As,9E)-9-Ethylidene-5,6,7,7Aα,8,8Aα,9,10-Octahydro-12β-Acetoxy-7-Acetylindolo[3,2,1-Ij]Pyrano[3,4-B][1,5]Naphthyridine-12Aα(12H)-Carboxylic Acid Methyl Ester
CAS No.	30809-23-5
Molecular Formula	C26H28N2O6
Molecular Weight	464.51 g/mol
Synonyms	Methyl (7As,9E)-9-ethylidene-12β-acetoxy-7-acetyl-5,6,7,7aα,8,8aα,9,10-octahydroindolo[3,2,1-ij]pyrano[3,4-b][1,5]naphthyridine-12aα(12H)-carboxylate; 12β-Acetoxy-7-acetyl-9-ethylidene-5,6,7,7aα,8,8aα,9,10-octahydroindolo[3,2,1-ij]pyrano[3,4-b][1,5]naphthyridine-12aα(12H)-carboxylic acid methyl ester; Alkaloid C-3 Acetate Methyl Ester; Vincamine derivative; Apovincaminic acid derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.