Description

(7As,9E)-9-Ethylidene-5,6,7,7Aα,8,8Aα,9,10-Octahydro-12β-Methoxy-7-Methylindolo[3,2,1-Ij]Pyrano[3,4-B][1,5]Naphthyridine-12Aα(12H)-Methanol is a complex, high-purity alkaloid derivative with a fused polycyclic structure. This compound is of significant interest for its potential as a key synthetic intermediate or a pharmacologically active scaffold in advanced research and development. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and novel drug discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a critical synthetic intermediate or a lead compound in the discovery of new therapeutic agents, particularly for central nervous system (CNS) or oncological targets.
• Medicinal Chemistry Studies: Used for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of novel drug candidates.
• Fine Chemical Synthesis: Employed as a building block for the multi-step synthesis of complex, high-value specialty chemicals and active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use as a tool compound or a probe in biochemical assays to study specific enzyme interactions or receptor binding.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis, natural product chemistry, and pharmacology.
• Contract Research Organizations (CROs): Supplied to CROs supporting drug discovery pipelines for pharmaceutical and biotech clients.

Basic Information

Product Name	(7As,9E)-9-Ethylidene-5,6,7,7Aα,8,8Aα,9,10-Octahydro-12β-Methoxy-7-Methylindolo[3,2,1-Ij]Pyrano[3,4-B][1,5]Naphthyridine-12Aα(12H)-Methanol
CAS No.	30809-22-4
Molecular Formula	C23H28N2O3
Molecular Weight	380.48 g/mol
Synonyms	12-Methoxyibogamine; 12-Methoxyibogamin-12-ol; Ibogamine, 12-methoxy-; 12-Methoxyibogamine (7α,9E)-isomer; 12-Hydroxy-12-methoxyibogamine; (7α,9E)-12-Methoxyibogamine; 12-Methoxyibogamin-12-ol (7α,9E)-form
EINECS	Contact for details

Quality Control

Our (7As,9E)-9-Ethylidene-5,6,7,7Aα,8,8Aα,9,10-Octahydro-12β-Methoxy-7-Methylindolo[3,2,1-Ij]Pyrano[3,4-B][1,5]Naphthyridine-12Aα(12H)-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, chromatographic data, and other relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere at 2-8°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.