Description

6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant intermediate and building block. This compound is valued for its role as a key synthetic precursor in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex alkaloids and other bioactive molecules.
• API Development: Used in research and development for creating new drug candidates, especially in neurological and cardiovascular therapeutic areas.
• Chemical Synthesis: Serves as a versatile precursor for constructing tetrahydroisoquinoline scaffolds in medicinal chemistry.
• Biochemical Research: Employed as a standard or reagent in studies involving enzyme inhibition or receptor binding assays.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals and advanced organic compounds.

Basic Information

Product Name	6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride
CAS No.	30740-95-5
Molecular Formula	C₁₂H₁₅NO₄·HCl
Molecular Weight	273.71 g/mol
Synonyms	6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride; 3-Carboxy-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6,7-Dimethoxy-3-carboxy-1,2,3,4-tetrahydroisoquinoline HCl; THIQ-3-COOH derivative; 30740-95-5; (3-Carboxy-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl) hydrochloride
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.