Description

Hexadecanoic-4,4-D2 Acid is a deuterium-labeled isotopologue of palmitic acid, a fundamental saturated fatty acid. This compound is specifically designed for use as an internal standard or tracer in advanced analytical and metabolic research, ensuring precise quantification and tracking. It is an essential material for researchers and quality control laboratories in the pharmaceutical, biotechnology, and analytical chemistry sectors who require high-purity isotopic standards for mass spectrometry (MS), nuclear magnetic resonance (NMR), and pharmacokinetic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Provides accurate quantification of palmitic acid and related metabolites in complex biological matrices like plasma, serum, and tissue samples.
• Metabolic Pathway Tracing: Used in stable isotope labeling studies to investigate lipid metabolism, β-oxidation, and biosynthetic pathways in vivo and in vitro.
• Pharmaceutical Research & Development: Supports drug metabolism and pharmacokinetics (DMPK) studies for compounds interacting with fatty acid pathways.
• Analytical Method Development: Serves as a critical reference material for validating and calibrating GC-MS and LC-MS methods in analytical laboratories.
• Biochemical Research: Facilitates studies on enzyme kinetics, protein-lipid interactions, and the role of palmitic acid in cellular signaling and disease models.
• Quality Control & Assurance: Acts as a certified reference material (CRM) for ensuring the accuracy and precision of analytical results in regulated environments.

Basic Information

Product Name	Hexadecanoic-4,4-D2 Acid
CAS No.	30719-28-9
Molecular Formula	C16H30D2O2
Molecular Weight	258.43 g/mol
Synonyms	Palmitic-4,4-d2 Acid; 4,4-Dideuteriohexadecanoic Acid; Hexadecanoic-d2 Acid; [4,4-2H2]Palmitic Acid; C16:0-d2; Deuterated Palmitic Acid; Isotopic Palmitic Acid; 1-Pentadecanecarboxylic-4,4-d2 Acid
EINECS	Contact for details

Quality Control

Our Hexadecanoic-4,4-D2 Acid is manufactured under controlled conditions to meet the stringent requirements of research and analytical applications. Each batch undergoes rigorous quality testing, including isotopic purity and chemical purity analysis by NMR, MS, and HPLC, to ensure consistent performance and traceability. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.