Description

4-Chloroisoquinolin-1-Amine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the isoquinoline core.
• Ligand and Catalyst Development: Employed in the creation of novel nitrogen-donor ligands for transition metal catalysis and coordination chemistry.
• Material Science Precursor: Acts as a building block for organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe Synthesis: Utilized to create tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	4-Chloroisoquinolin-1-Amine
CAS No.	30598-04-0
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	1-Amino-4-chloroisoquinoline; 4-Chloro-1-isoquinolinamine; 4-Chloro-isoquinolin-1-ylamine; 4-Chloro-1-aminoisoquinoline; 1-Isoquinolinamine, 4-chloro-; 30598-04-0; 4-Chloro-1-isoquinolylamine
EINECS	Contact for details

Quality Control

Our 4-Chloroisoquinolin-1-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity determination, and is supplied with a comprehensive Certificate of Analysis (COA). We adhere to cGMP guidelines where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.