Description

(2R)-1,2,6,6Aα,12,12Aα-Hexahydro-2-(1-Hydroxy-1-Methylethyl)-8,9-Dimethoxy[1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-6-One is a high-purity, complex heterocyclic compound with significant potential as a key intermediate in advanced organic synthesis. Its intricate fused ring system makes it a valuable building block for research and development in pharmaceutical discovery and fine chemical manufacturing. This compound is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), natural product derivatives, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel drug candidates, particularly in therapeutic areas targeting complex biological pathways.
• Natural Product Analog Synthesis: Used in medicinal chemistry to create analogs of complex natural products for structure-activity relationship (SAR) studies.
• Chemical Research & Development: Acts as a sophisticated starting material or reference standard in academic and industrial research exploring new chemical entities and reaction methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, low-volume specialty chemicals for advanced technological applications.
• Reference Standard: Provides a high-purity benchmark for analytical method development, quality control, and regulatory submissions in pharmaceutical development.

Basic Information

Item	Details
Product Name	(2R)-1,2,6,6Aα,12,12Aα-Hexahydro-2-(1-Hydroxy-1-Methylethyl)-8,9-Dimethoxy[1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-6-One
CAS No.	30462-22-7
Molecular Formula	C24H26O7
Molecular Weight	426.46 g/mol
Synonyms	(-)-Rocaglaol; Rocaglaol; Rocaglaol, (-)-; 1,2,6,6Aα,12,12Aα-Hexahydro-2-(1-hydroxy-1-methylethyl)-8,9-dimethoxy[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6-one, (2R)-; AG-L-59687; L-59687; (-)-Rocaglaol (Roc-A); Roc-A
EINECS	Contact for details

Quality Control

Our (2R)-1,2,6,6Aα,12,12Aα-Hexahydro-2-(1-Hydroxy-1-Methylethyl)-8,9-Dimethoxy[1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.