Description

Coumarin, 3,7,8-Trihydroxy-4-Methyl- (8Ci) is a multi-hydroxylated derivative of the coumarin family, characterized by its specific substitution pattern which imparts unique chemical reactivity and biological activity. This compound is valued for its role as a versatile synthetic intermediate and a key structural motif in the development of bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications in drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its natural product-inspired structure for bioactivity.
• Fine Chemical Synthesis: Acts as a precursor for dyes, fluorescent markers, and other specialty organic compounds.
• Biochemical Research: Employed in studies of enzyme inhibition, antioxidant activity, and other structure-activity relationship (SAR) investigations.
• Cosmetic Ingredient Research: Explored for potential use in skincare formulations due to the antioxidant properties associated with polyphenolic structures.
• Academic & Industrial R&D: A key material for organic chemists in methodological studies and the construction of complex molecular libraries.

Basic Information

Product Name	Coumarin, 3,7,8-Trihydroxy-4-Methyl- (8Ci)
CAS No.	30404-45-6
Molecular Formula	C10H8O5
Molecular Weight	208.17 g/mol
Synonyms	3,7,8-Trihydroxy-4-methylcoumarin; 4-Methyl-3,7,8-trihydroxy-2H-chromen-2-one; 3,7,8-Trihydroxy-4-methyl-2H-1-benzopyran-2-one; NSC 407347; 4-Methylfraxetin; 8-Hydroxy-4-methyl-7,8-dihydroxycoumarin (ambiguous); 4-Methyl-7,8-dihydroxycoumarin (common misnomer)
EINECS	Contact for details

Quality Control

Our Coumarin, 3,7,8-Trihydroxy-4-Methyl- (8Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to minimize exposure to atmospheric humidity. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.