Description

Bitolterol CAS NO 30392-40-6 is a synthetic adrenergic bronchodilator belonging to the class of β-2 adrenergic receptor agonists. This compound is of significant interest in pharmaceutical research and development for its potential therapeutic effects. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of respiratory medications. Its specific pharmacological profile makes it a key intermediate or reference standard in the study of airway diseases.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel bronchodilator medications.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Biochemical Studies: Employed in pharmacological and biochemical research to study β-2 adrenergic receptor mechanisms and signal transduction pathways.
• Respiratory Drug Development: Investigated for potential applications in formulating treatments for asthma, chronic obstructive pulmonary disease (COPD), and other bronchospastic conditions.

Basic Information

Product Name	Bitolterol
CAS No.	30392-40-6
Molecular Formula	C28H37NO5
Molecular Weight	467.60 g/mol
Synonyms	Bitolterol; N-tert-Butylarterenol 3,4-bis(p-toluate); 4-[2-(tert-Butylamino)-1-hydroxyethyl]-1,2-phenylene bis(4-methylbenzoate); Colterol 3,4-bis(p-toluate); MJ 9184-1; Win 32,428; α-[(tert-Butylamino)methyl]-3,4-dihydroxybenzyl alcohol 3,4-bis(4-methylbenzoate)
EINECS	Contact for details

Quality Control

Our Bitolterol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling using advanced techniques like HPLC and GC. We provide Certificates of Analysis (COA) with detailed specifications for traceability and quality assurance, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect the light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.